NMN Plus – 3pk AlivebyNature60 Capsules, 475 mg each

$126.95

Out of stock

Product Description

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Not in stock at this time. We have halted production of this product and do not know if we will resume production in 2018. NMN PURE, which has the same quantity of NMN, with no other ingredients, is expected to begin shipping December 12, 2017.

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INGREDIENTS  in NMN PLUS

In addition to NMN, which is the  IMMEDIATE PRECURSOR used by our bodies to produce NAD+, we include the other 3  major precursors:

  • NAM (Nicotinamide)
  • Tryptophan
  • NA (Niacin)

NIACIN  is well known to cause an uncomfortable “Niacin Flush in some people.  We used a dosage that is about 1/2 of what  research shows affects less than 1% of users.  Read more about this, and what you can do to minimize niacin flush.

For those that want ONLY NMN, we offer  NMN PURE, which contains 125 mg of NMN per capsule and nothing else, but that product will not be available to ship until Dec 8, 2017.

Obviously, it would be easier to produce only the single ingredient NMN PURE, but we are so convinced the proven NAD+ boosting ability of the secondary precursors make this product more effective, we have worked over 12 months on research, development, and testing, in addition to the expense, to offer this Complete NAD+ Booster.

Read our Dosage Recommendations here

Read more about the ingredients of NMN PLUS  below.

ABOUT NMN

In this 2016  study by David Sinclair, Mice given NMN for 12 months exhibited better glucose control, increased energy, less weight gain, better mobility and overall health.

According to Dr Sinclair:

  • “NMN was able to mitigate most age-associated physiological declines in mice”
  • “treatment of old mice with NMN reversed all of these biochemical aspects of aging”
  • “enhancing NAD+ biosynthesis by using NAD+ intermediates, such as NMN and NR, is expected to ameliorate age-associated physiological decline”

 

mouse-single-dose
The red line in chart at left shows oral NMN supplement in mice is quickly absorbed from the gut into blood circulation within 2–3 min and then cleared from blood circulation into tissues within 15 minutes.

The blue line shows NAD+ levels begin to increase significantly in tissue within 15 minutes.

 

 

This second chart shows levels of a double labeled NAD+ (C13-d-nad+) in liver and soleus muscle at 10 and 30 minutes after oral administration of double labeled NMN.

This clearly shows the NMN makes its way through the liver and into muscle in 30 minutes.

Niacin, Nicotinamide, and Tryptophan can also be converted to NAD+ through different pathways, but are less efficient precursors.

 

HUMAN STUDIES – LONG TERM SUPPLEMENTATION WITH NMN

The first clinical trial of NMN in humans is currently underway by an international collaborative team between Keio University School of Medicine in Tokyo and Washington University School of Medicine (R).

Participants are 50 healthy women between 55 and 70 years of age with slightly high blood glucose,BMI and triglyceride levels.

Using a dose of 2 capsules of 125mg NMN per day over a period of 8 weeks, researchers are testing for:

  • change in insulin sensitivity
  • change in beta-cell function
  • works to control blood sugar
  • blood vessels dilate
  • effects of NMN on blood lipids
  • effects of NMN on body fat
  • markers of cardiovascular and metabolic health

According to the study:

“Data from studies conducted in rodents have shown that NMN supplementation has beneficial effects on cardiovascular and metabolic health, but this has not yet been studied in people”

Testing of metabolic parameters will continue for 2 years after supplementation has ended, so final results will not be published for some time yet, but preliminary results are expected to be announced in early 2018.

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to read more about NMN  and other NAD+ precursors  Click here

to read more about NAD+  Click here

There have been dozens of studies in mice showing effectiveness at treating many chronic health problems.

The first clinical study on NMN with humans is underway now.

** These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

 

QUALITY ASSURANCE
Below is the assay we received from an independent lab certifying that this product includes Nicotinamide Mononucleotide of 98% purity.

We are also in the process of securing NSF certification.  NSF pulls bottles of finished product randomly and tests to ensure the finished product has the ingredients as claimed on the label, so you can be assured this product is what we advertise.

References:

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