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Best Anti-aging supplements other than NR and NMN

Geroprotectors are substances that support healthy aging, slow aging, or extend healthy life. Sometimes people refer to them as “aging suppressants,” “anti-aging drugs,” “gerosuppressants,” “longevity therapeutics,” “senolytics,” or “senotherapeutics.” They include various foods, nutraceuticals (supplements), and pharmaceuticals (drugs). Unfortunately none comes close to realizing the age-old aspiration of ending aging altogether (yet), but some may make […]

Nicotinamide mononucleotide inhibits JNK activation to reverse Alzheimer disease.

Study published here Highlights   NMN improved behavioral measures of cognitive impairments in AD-Tg mice.   NMN decreased β-amyloid production, amyloid plaque burden, synaptic loss, and inflammatory responses in AD-Tg mice.   NMN reduced JNK activation in AD-Tg mice.   NMN regulated the expression of APP cleavage secretase in AD-Tg mice. Abstract Amyloid-β (Aβ) oligomers […]

Can NMN really reverse Aging? (backup)

As we age, our levels of the Co-enzyme Nicotinamide Adenine Dinucleotide NAD+ drop significantly in multiple organs in mice and humans  (5,8,10). NAD+ decrease is described as a trigger in age-associated decline(23), and perhaps even the key factor in why we age (5). In 2013, research published by Dr David Sinclair demonstranted that short term supplementation with […]