DO NOT TAKE MORE THAN ONE CAPSULE ON YOUR FIRST EXPERIENCE WITH NMN PLUS! We include a very small dose of Niacin in the formula for NMN PLUS. NIACIN is well known to cause an uncomfortable “Niacin Flush“ in some people. We used a dosage that is about 1/2 of what research shows affects […]
Geroprotectors are substances that support healthy aging, slow aging, or extend healthy life. Sometimes people refer to them as “aging suppressants,” “anti-aging drugs,” “gerosuppressants,” “longevity therapeutics,” “senolytics,” or “senotherapeutics.” They include various foods, nutraceuticals (supplements), and pharmaceuticals (drugs). Unfortunately none comes close to realizing the age-old aspiration of ending aging altogether (yet), but some may make […]
This is the transcript from Ben’s podcast you can listen to here: Ben: Hey folks, it’s Ben Greenfield, and I wanna tell you about an article I recently read in Scientific American. This article was called “Beyond Resveratrol: The Anti-Aging Nad Fad”, and NAD referring to NAD. And what this article includes, among many other things, is, for example, […]
However, in its oxidized form (NAD+), NAD is also a cofactor for sirtuin enzymes and poly-ADP-ribose polymerase (PARP), both of which consume NAD in the course of removing acyl groups from and adding poly-ADP to proteins, respectively. Sirtuins and PARP thereby regulate cellular functions ranging from gene expression and DNA damage repair to fatty acid […]
In 2012, Research published by Dr Sinclair of Harvard stunned researchers by showing that short term supplementation with Nicotinamide Mono-Nucleotide (NMN) reversed many aspects of aging, making the cells of old mice resemble those of much younger mice, and greatly improving their health. Since then Chromadex has been marketing a related product named Nicotinamide Riboside […]
The .pdf version of this research can be found at https://www.researchgate.net/ 1. Introduction Inflammation, a basic biological response against invading pathogens, contributes to repairing damage and preventing further tissue or cell injury (Medzhitov, 2008). However, when the inflammatory response cannot be appropriately attenuated, multi-organ failure or chronic inflammation can develop (Medzhitov, 2008). In this sense, increasing […]
Inflammation influence on aging process itself, not just age related disease We know NAD+ levels go down dramatically as we age. Many recent and ongoing research studies are investigating protocols for boosting NAD+ levels in elderly individuals to combat both disease and infirmities related to aging. Supplementing with Nicotinamide Riboside and/or NMN are […]
As we age, our levels of the Co-enzyme Nicotinamide Adenine Dinucleotide NAD+ drop significantly in multiple organs in mice and humans (5,8,10). NAD+ decrease is described as a trigger in age-associated decline(23), and perhaps even the key factor in why we age (5). In 2013, research published by Dr David Sinclair demonstranted that short term supplementation with […]
Nicotinamide Riboside (NR) is a form of vitamin B3 closely related to Niacin that is showing great promise for it’s ability to raise NAD+ levels in older humans, back to the levels normally found in youth to prevent and repair damage to various organs in the body. NAD+ is a key co-enzyme that enables the mitochondria to […]
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in the cells of all living creatures (3,4) and is critical for communication between the cell nucleus and the mitochondria that power the cells (5,6,7) LOWER NAD+ LEVELS AS WE AGE Everyone experiences lower NAD+ levels throughout the body as we age, effecting the communication within every […]
