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Best Anti-aging supplements other than NR and NMN

Geroprotectors are substances that support healthy aging, slow aging, or extend healthy life. Sometimes people refer to them as “aging suppressants,” “anti-aging drugs,” “gerosuppressants,” “longevity therapeutics,” “senolytics,” or “senotherapeutics.” They include various foods, nutraceuticals (supplements), and pharmaceuticals (drugs). Unfortunately none comes close to realizing the age-old aspiration of ending aging altogether (yet), but some may make […]

Ben Greenfield on NAD+

This is the transcript from Ben’s podcast you can listen to here: Ben: Hey folks, it’s Ben Greenfield, and I wanna tell you about an article I recently read in Scientific American.  This article was called “Beyond Resveratrol: The Anti-Aging Nad Fad”, and NAD referring to NAD.  And what this article includes, among many other things, is, for example, […]

The Ketone body β-Hydroxybutyrate a key signaling metabolite in disease and aging

However, in its oxidized form (NAD+), NAD is also a cofactor for sirtuin enzymes and poly-ADP-ribose polymerase (PARP), both of which consume NAD in the course of removing acyl groups from and adding poly-ADP to proteins, respectively. Sirtuins and PARP thereby regulate cellular functions ranging from gene expression and DNA damage repair to fatty acid […]

Does Basis still use Nicotinamide Riboside (NR) from Chromadex?

In 2012, Research published by Dr Sinclair  of Harvard stunned researchers by showing that short term supplementation with Nicotinamide Mono-Nucleotide (NMN) reversed many aspects of aging, making the cells of old mice resemble those of much younger mice, and greatly improving their health. Since then Chromadex has been marketing a related product named Nicotinamide Riboside […]

Mitochondrial dysfunction and the inflammatory response

The .pdf version of this research can be found at https://www.researchgate.net/ 1. Introduction Inflammation, a basic biological response against invading pathogens, contributes to repairing damage and preventing further tissue or cell injury (Medzhitov, 2008). However, when the inflammatory response cannot be appropriately attenuated, multi-organ failure or chronic inflammation can develop (Medzhitov, 2008). In this sense, increasing […]

Inflammation Is a key participant in all aging and disease

Inflammation influence on aging process itself, not just age related disease   We know NAD+ levels go down dramatically as we age.   Many recent and ongoing research studies are   investigating protocols for boosting NAD+ levels in elderly individuals to combat both disease and infirmities related to aging.  Supplementing with Nicotinamide Riboside and/or NMN are […]

Can NMN really reverse Aging? (backup)

As we age, our levels of the Co-enzyme Nicotinamide Adenine Dinucleotide NAD+ drop significantly in multiple organs in mice and humans  (5,8,10). NAD+ decrease is described as a trigger in age-associated decline(23), and perhaps even the key factor in why we age (5). In 2013, research published by Dr David Sinclair demonstranted that short term supplementation with […]

Supplementation to correct NAD+ deficiency repairs vision damage in Mice

Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in the cells of all living creatures (3,4) and is critical for communication between the cell nucleus and the mitochondria that power the cells (5,6,7) LOWER NAD+ LEVELS AS WE AGE Everyone experiences lower NAD+ levels throughout the body as we age, effecting the communication within every […]