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5 Day Fast – Using the Fast Mimicking Diet

Recently I began a 3-day fast, which then got extended to 5 days. The intention was to use the “Tim Ferriss method” (described here). Essentially accelerating the shift from glucose burning to fat burning as quick as possible, avoiding the negative physical feelings associated with the transition period. (60 second video primer on ketones if you’re not familiar). However, in […]

Proof that Ketogenic Diets Increase NAD+ to Curb Inflammation and prevent brain degeneration

  Ketogenic diets — extreme low-carbohydrate, high-fat regimens that have long been known to benefit epilepsy and other neurological illnesses — may work by lowering inflammation in the brain, according to new research by UC San Francisco scientists. The UCSF team has discovered a molecular key to the diet’s apparent effects, opening the door for […]

How the war on Cholesterol caused our diabetes epidemic

Cholesterol is a molecule required by every cell of the body in fairly large amounts. It can be easily synthesised by these cells, or taken up by them from LDL and other ApoB lipoproteins, but cannot be broken down. Cholesterol is not soluble in water, and thus must be carried through the blood on lipoprotein […]

Glucose Ketone Index (GKI) – What Ratio Do I need for Nutritional Ketosis Benefits?

Generally these blog posts are a result of scratching my own itch (answering my own question), and this post is no different. At the time of writing this, I’m doing a 5-day fast, and wanted to understand the readings I’m getting for my blood glucose and blood ketone levels. Initially I thought that blood ketones […]

Low Carb Best for health and weight loss

High-Fat Diet Doesn’t Cause Obesity I wrote the other day about the less-than-optimal control animals and humans used in fasting and calorie-restriction studies. Partly this is due to the bad food that most people eat, as well as the substandard lab food that rats and mice eat. A similar problem exists in other diet experiments […]

Keto-Fasting and life extension

The starvation hormone increases lifespan   In the last post, I discussed the growth-longevity trade-off in the context of intermittent fasting. In this post, I’ll discuss some further evidence for the connection between growth and lifespan. A very neat paper shows that transgenic mice made to overexpress a certain hormone live much longer than wild […]

Keto diet creates beta hydroxybutyrate (BHB) that extends health and lifespan

Eating a very low-carbohydrate diet results in the production of ketones, which the body uses as an alternative fuel source; hence very low-carbohydrate diets (VLCKD) diets are called ketogenic. The liver makes ketones from fatty acids when glycogen (the storage form of carbohydrate) has been depleted, hence going without carbohydrates, or fasting altogether (for around […]