Archive | August, 2016

Nicotinamide Riboside shown to increase NAD+ in first clinical study with humans

Nicotinamide Riboside  (Niagen) has shown the ability to elevate the co-enzyme NAD+ levels in clinical studies with Mice many times, but in a series of research described in this PHD thesis, has now been proven to have the same effect in humans. Several experiments were carried testing response to NAD+ levels in both human and […]

New Study finds Nicotinamide Riboside safe at typical dosages

A clinical study was published January 2016 on the safety and side effects  of Nicotinamide Riboside in the HET Journal (Human and Experimental Toxicology), an international peer reviewed journal. Although naturally occurring in trace amounts in some foods such as milk and beer, Nicotinamide riboside (NR) is a recently discovered form of vitamin B3. It is being studied […]

Quercetin, not caffeine is neuroprotective ingredient in coffee

An interesting study was carried out by researchers of the Kinsmen Laboratory of Neurological Research, University of British Columbia. They set out to determine which component of coffee is responsible for its alleged neuroprotective effects. Several epidemiologic studies have indicated that coffee consumption has a protective effect against Parkinson disease (PD) and Alzheimer disease (AD). […]

Heart Attack risk cut by Omega 3 fats

The health benefits of long-chain omega-3 fatty acids — docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) – are well known. One large trial in patients with heart disease showe d that supplementing with 1 gram of omega-3 per day reduced their risk of death by 20%. However, not all studies agree (1, 2). Recently, a large […]

What are the best No Calorie Sugar replacements

Excessive sugar consumption is suspected to be one of the main causes of obesity. Rather than making the effort to eat healthy whole foods, many people look for an easy solution like popping some Garcinia Cambogia pills,using zero-calorie (non-nutritive) sweeteners instead of added sugar. They are supposed to provide a sweet taste without any of […]

Cancer risks linked to body fat

Cancer is one of the leading causes of death. Earlier this year, the International Agency for Research on Cancer (IARC) assembled an international group of experts to assess the effects of excess fat on cancer risk. Recently, they published an overview of their conclusions in The New England Journal of Medicine. Here is a summary of […]

Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition

This study by Dr Charles Brener published here  in 2008. As schematized in Figure 1, the reason that a poor diet can produce a requirement for Na and Nam is that Trp, Na, and Nam are all NAD+ precursors (7). Trp is converted to NAD+ through an eight-step de novo pathway (Figure 2), so termed because […]